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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Heavy-chain antibody ： ウィキペディア英語版 Heavy-chain antibody A heavy-chain antibody is an antibody which consists only of two heavy chains and lacks the two light chains usually found in antibodies. In common antibodies, the antigen binding region consists of the variable domains of the heavy and light chains (VH and VL). Heavy-chain antibodies can bind antigens despite having only VH domains. This observation has led to the development of a new type of antibody fragments with potential use as drugs, so-called single-domain antibodies. ==Discovery== In 1989 a group of biologists led by Raymond Hamers at the Free University Brussels investigated the immune system of dromedaries. In addition to the expected four-chain antibodies, they identified simpler antibodies consisting only of two heavy chains. This discovery was published in ''Nature'' in 1993.〔 In 1995 a research team at the University of Miami found a different type of heavy-chain antibodies in sharks. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Heavy-chain antibody」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.